That has spread to other parts of the body or cannot be removed by surgery, and whose tumor is KRAS G12C positive, and who have received at least one prior treatment.1




Take LUMAKRAS® once daily by mouth with or without food.1

The recommended dose of LUMAKRAS® is 960 mg (three 320 mg tablets or eight 120 mg tablets) taken orally once daily.2 Speak with your doctor if you have any questions or experience a side effect.

There are two different LUMAKRAS® tablets2,3

LUMAKRAS® 320 mg tablets

LUMAKRAS® 320 mg tablets have a beige color. They come in one bottle containing 90 tablets.


LUMAKRAS® 120 mg tablets

LUMAKRAS® 120 mg tablets have a yellow color. They come in one bottle containing 240 tablets.

Please make sure you take the right number of tablets.

Tablets seen on screen may not reflect actual size.

  • Take LUMAKRAS® exactly as your healthcare provider tells you to take it. Do not change your dose or stop taking LUMAKRAS® unless your healthcare provider tells you to.

  • Take LUMAKRAS® 1 time each day, at about the same time each day.


Swallow LUMAKRAS® tablets whole. Do not chew, crush, or split tablets.

If you cannot swallow LUMAKRAS® tablets whole:1

  • Place your daily dose of LUMAKRAS® in a glass of 4 ounces (120 mL) of non-carbonated room temperature water without crushing the tablets. Do not use any other liquids.

  • Stir until the tablets are in small pieces (the tablets will not completely dissolve). The color of the mixture may be pale yellow to bright yellow.

  • Drink the LUMAKRAS® and water mixture right away or within 2 hours of preparing. Do not chew pieces of the tablet.

  • Rinse the glass with an additional 4 ounces (120 mL) of water and drink to make sure that you have taken the full dose of LUMAKRAS®.

  • If you do not drink the mixture right away, stir the mixture again before drinking.


I take my LUMAKRAS® pills once a day.

- Laurie, current LUMAKRAS® patient

Patient testimonials represent individuals' experiences with LUMAKRAS®. Results may vary.


  • If you take an antacid medicine such as Tums®, take LUMAKRAS® either 4 hours before or 10 hours after the antacid. Speak to your healthcare provider if you are on PPIs or H2 blockers
  • If you miss a dose of LUMAKRAS®, take the dose as soon as you remember. If it has been more than 6 hours, do not take the dose. Take your next dose at your regularly scheduled time the next day. Do not take 2 doses at the same time to make up for a missed dose
  • If you vomit after taking a dose of LUMAKRAS®, do not take an extra dose. Take your next dose at your regularly scheduled time the next day