That has spread to other parts of the body or cannot be removed by surgery, and whose tumor is KRAS G12C positive, and who have received at least one prior treatment.1

ABOUT
KRAS G12C
IN NSCLC

LUMAKRAS® is not intended for use in children.

What is KRAS?

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KRAS is a protein that we all have in our bodies. Proteins are required for the structure and function of the body’s cells, tissues, and organs.1

light_on_off_switch

The KRAS protein works like an on/off switch, relaying messages that tell cells when to grow and when to stop growing.2

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“ Biomarker testing was important for me to know the next step to take. If it wasn’t for this test, I wouldn’t be on LUMAKRAS®.”

- Laurie, current LUMAKRAS® patient

Patient testimonials represent individuals’ experiences with LUMAKRAS®. Results may vary.

WHAT IS KRAS G12C IN NSCLC?

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KRAS G12C is a mutation of the KRAS protein. Sometimes a protein can become mutated (altered) and function abnormally.2

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KRAS G12C causes the on/off switch to get stuck in the “on” position, leading to continuous and uncontrollable cell growth that can form tumors.3

“ I have heard of KRAS G12C so when I found out that LUMAKRAS® was available and that it targets this mutation, then that’s when I got excited! ”

- Laurie, current LUMAKRAS® patient

Patient testimonials represent individuals' experiences with LUMAKRAS®. Results may vary.

KRAS G12C IS
FOUND IN
1
IN
8
NSCLC PATIENTS4

HOW CAN BIOMARKER TESTING HELP ME WITH MY NSCLC TREATMENT?

The only way to know if you have KRAS G12C is by asking your doctor for a biomarker test. Biomarkers are molecules inside your body that can tell your doctor what kind of NSCLC you may have.5,6

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One of the most common NSCLC biomarkers is KRAS G12C.

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WHAT DO MY BIOMARKER TEST
RESULTS MEAN?
If you have the KRAS G12C biomarker, it could mean there’s a targeted treatment option specially designed for your type of lung cancer.7

The only way to know if you have KRAS G12C is by asking your doctor for a biomarker test. Biomarkers are molecules inside your body that can tell your doctor what kind of NSCLC you may have.5,6

HOW WILL MY DOCTOR TEST FOR KRAS G12C?

  • Your doctor can test you for the KRAS G12C biomarker by using a biopsy8
  • A biopsy can be done by using either a tissue from the tumor (tissue biopsy) or a blood test (liquid biopsy)8
  • Your doctor will determine which test is right for you8
green-round-icon

Ask your doctor about a KRAS G12C biomarker test
If your biomarker test found that you have KRAS G12C, LUMAKRAS® may be an option for you7

NEXT: ABOUT LUMAKRAS®