ABOUT KRAS G12C

What is KRAS G12C?

1_kras

1. We all have a protein in our body called KRAS. Proteins are required for the structure and function of the body’s cells, tissues, and organs.1

light_on_off_switch

2. The KRAS protein works like an on/off switch, relaying messages that tell cells when to grow and when to stop growing.2

3_mutated_protein

3. Sometimes a protein can become mutated (altered) and function abnormally. KRAS G12C is a mutation of the KRAS protein.2

light_on_switch

4. KRAS G12C causes the on/off switch to get stuck in the “on” position, leading to continuous and uncontrollable cell growth that can form tumors.3

1 in 8

KRAS G12C IS FOUND IN
1 OUT OF EVERY 8 NSCLC PATIENTS.4

DO I HAVE KRAS G12C?

5_biomarkers

1. There are many types of biomarkers.4 Biomarkers are molecules inside your body that can tell your doctor what kind of NSCLC you may have.5

6_G12C

2. One of the most common NSCLC biomarkers is KRAS G12C.4

1_in_8_patients

3. In fact, 1 in 8 patients with NSCLC have this biomarker.4

8_targetedG12C

4. If you have the KRAS G12C biomarker, it could mean there’s a targeted treatment option specially designed for your type of lung cancer.6

9_biomarker_test

5. The only way to know if you have the KRAS G12C biomarker is
with a biomarker test.7

ask_your_doctor

Ask your doctor if you’ve received a KRAS G12C biomarker test.
LUMAKRAS™ may be an option if you tested positive for KRAS G12C.6